{"title":"Mitochondrial Energy \u0026 Healthy Aging","description":null,"products":[{"product_id":"spermidine-wheat-germ-extract","title":"Spermidine","description":"Spermidine first isolated from semen or sperm, is a water-soluble polyamine ingredient that occurs naturally in all tissues of our human bodies and also found in many other organisms like animals, plants, and typical dietary foods. Spermidine is able to penetrate biological membranes and believed to be beneficial to cell renewal and anti-aging purposes.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eSpermidine is a best known for activating autophagy. Autophagy is the process that the body uses to get rid of damaged cells and maintenance of healthy cells. Natural autophagy decreases over time, and boosting it back to youthful levels with spermidine has shown incredible results.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eStudies have shown that spermidine may delay ageing in humans, support the reduction of age-related diseases, support cognition and heart health, promote hormonal balance, support liver health, provide anti-inflammatory benefits, improve hair growth and strengthen nails. Epidemiological studies have correlated higher spermidine levels with longer life.","brand":"acerchem","offers":[{"title":"1%","offer_id":46394854670621,"sku":"EZ891238a","price":280.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0811\/5047\/6573\/files\/istockphoto-1744863356-612x612.jpg?v=1711620434"},{"product_id":"pqq","title":"VitaliQ™ PQQ Disodium Salt","description":"\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003ePQQ, or Pyrroloquinoline quinone, is a crucial cofactor for a vitamin-like substance that the human body cannot synthesize. It is naturally present in soil, certain soil bacteria, and even interstellar dust. Plants acquire PQQ from soil and bacteria, passing it up the food chain. Humans and animals obtain PQQ through their diets, with newborns receiving a significant amount through breast milk.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003ePQQ plays a multifaceted role in promoting health and vitality. It aids in the generation of new mitochondria, enhances cellular energy production, addresses age-related skin concerns, and provides anti-aging effects for the liver and heart. Its applications extend to dietary supplements, functional foods, medical foods, and beverages.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch1 class=\"MsoNormal\"\u003e\n\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003e\u003cspan style=\"font-family: Calibri;\"\u003eThe Mechanism of PQQ in the Body\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/h1\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eTo understand how PQQ promotes our health, it's essential to first discuss the role of mitochondria. Known as the cell's powerhouse, mitochondria generate energy through cellular respiration and are crucial for the energy metabolism of nearly every cell in the body. They produce the majority of the energy required for optimal health and performance.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eAdditionally, mitochondria play a key role in maintaining a healthy mood balance. They are involved in the synthesis, storage, and trafficking of certain neurotransmitters, including serotonin, dopamine, and norepinephrine, which are vital for regulating mood, emotions, and overall mental well-being.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eIn humans, supplementation with PQQ has been shown to enhance peak oxygen consumption and stimulate mitochondrial biogenesis by increasing the levels of PGC-1\u003c\/span\u003e\u003cspan style=\"font-family: 宋体;\"\u003eα \u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003eprotein. PQQ supports mitochondrial function, meaning it positively interacts with genes that are directly involved in maintaining mitochondrial health.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch1 class=\"MsoNormal\"\u003e\n\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003e\u003cspan style=\"font-family: Calibri;\"\u003eExploring the Diverse Benefits of PQQ\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/h1\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003e\u003cstrong\u003eMitochondrial Energy Optimization:\u003c\/strong\u003e PQQ protects delicate mitochondrial DNA from oxidative stress and encouraging mitochondrial biogenesis, the creation of new mitochondria.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003e\u003cstrong\u003eBrain Health:\u003c\/strong\u003e A study used logistic regression to examine cognitive changes between a placebo group and a group that received 20 mg of PQQ over a 12-week period. The results indicated significant improvements in cognitive abilities, such as memory, executive speed, and flexibility, with younger adults experiencing faster benefits.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003e\u003cstrong\u003eSupport for Sleep Quality:\u003c\/strong\u003e PQQ's capacity to mitigate DNA damage and oxidative stress during sleep deprivation is associated with its antioxidant properties. These properties may activate SIRT1 to eliminate excessive reactive oxygen species (ROS), thus contributing to neuronal protection and facilitating sleep recovery.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003e\u003cstrong\u003eImprovement in Skin Conditions: \u003c\/strong\u003eThe present study has demonstrated that orally ingested PQQ improves skin conditions because less water is lost from the skin’s surface, and the appearance of wrinkles and pigmentation is reduced in humans. \u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003e\u003cstrong\u003eProtection for Liver Health: \u003c\/strong\u003eIn a study investigating liver health, PQQ partly reversed damage from Bmi-1 deletion, offering therapeutic benefits like promoting proliferation, inhibiting senescence, and reducing oxidative stress.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003e\u003cstrong\u003eAnti-Aging Potential: \u003c\/strong\u003eA growing body of research suggests that reducing cellular senescence may lead to increased healthspan and lifespan. A team of researchers from China and Italy found that when PQQ was applied to human cells in culture, it delayed cellular senescence.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003e\u003cspan style=\"font-family: Calibri;\"\u003e\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch1 class=\"MsoNormal\"\u003e\n\u003cspan style=\"color: rgb(255, 42, 0);\"\u003e\u003cstrong\u003e\u003cspan style=\"font-family: Calibri;\"\u003eSafety Profile of PQQ Supplements\u003c\/span\u003e\u003c\/strong\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\n\u003c\/h1\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan\u003e\u003cspan style=\"font-family: Calibri;\"\u003eNo adverse effects have been reported in the studies reviewed. However, it's essential to note that PQQ supplements differ from dietary sources, with higher concentrations and specific production methods. The recommended daily dosage for adults is up to 20 mg, except for pregnant or breastfeeding women, to ensure safety and efficacy.\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan style=\"color: rgb(179, 179, 179);\"\u003e\u003cspan style=\"font-family: Calibri;\"\u003eReference\u003c\/span\u003e\u003cspan style=\"font-family: 宋体;\"\u003e：\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan style=\"color: rgb(179, 179, 179);\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e[1] \u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-family: Calibri;\"\u003eJonscher, Karen R et al. \u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e“\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003ePyrroloquinoline-Quinone Is More Than an Antioxidant: A Vitamin-like Accessory Factor Important in Health and Disease Prevention.\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e”\u003c\/span\u003e \u003cspan style=\"font-family: Calibri;\"\u003eBiomolecules vol. 11,10 1441. 30 Sep. 2021\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan style=\"color: rgb(179, 179, 179);\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e[2] \u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-family: Calibri;\"\u003eHuang Y, Chen N, Miao D. \u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e“\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003eBiological effects of pyrroloquinoline quinone on liver damage in Bmi-1 knockout mice.\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e”\u003c\/span\u003e \u003cspan style=\"font-family: Calibri;\"\u003eExp Ther Med. 2015 Aug;10(2):451-458.\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan style=\"color: rgb(179, 179, 179);\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e[3] \u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-family: Calibri;\"\u003eGao, Ying et al. \u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e“\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003ePyrroloquinoline quinone (PQQ) protects mitochondrial function of HEI-OC1 cells under premature senescence.\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e”\u003c\/span\u003e  \u003cspan style=\"font-family: Calibri;\"\u003enpj aging vol. 8,1 3. 19 Apr. 2022\u003c\/span\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp class=\"MsoNormal\"\u003e\u003cspan style=\"color: rgb(179, 179, 179);\"\u003e\u003c!-- [if !supportLists]--\u003e\u003cspan style=\"mso-list: Ignore;\"\u003e[4] \u003c\/span\u003e\u003c!--[endif]--\u003e\u003cspan style=\"font-family: Calibri;\"\u003eHao, Jingjing et al. \u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e“\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003ePyrroloquinoline quinone delays inflammaging induced by TNF-\u003c\/span\u003e\u003cspan style=\"font-family: 宋体;\"\u003eα \u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003ethrough the p16\/p21 and Jagged1 signalling pathways.\u003c\/span\u003e\u003cspan style=\"font-family: Calibri;\"\u003e”\u003c\/span\u003e \u003cspan style=\"font-family: Calibri;\"\u003eClinical and experimental pharmacology \u0026amp; physiology vol. 47,1 (2020): 102-110\u003c\/span\u003e\u003c\/span\u003e\u003cspan\u003e\u003c\/span\u003e\u003c\/p\u003e","brand":"Acerchem","offers":[{"title":"99% \/ 25kg\/drum \/ Acerchem","offer_id":46394859192605,"sku":"EZ891214b","price":900.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0811\/5047\/6573\/files\/clear-1205688_1920.jpg?v=1711618295"},{"product_id":"nicotinamide-adenine-dinucleotide_reduced-nadh","title":"Nicotinamide Adenine Dinucleotide_Reduced (NADH)","description":"\u003cdiv class=\"flex flex-grow flex-col max-w-full\" data-mce-fragment=\"1\"\u003e\n\u003cdiv data-message-author-role=\"assistant\" data-message-id=\"d4f8fa45-1838-4dd6-9b56-c89e41a87bd4\" class=\"min-h-[20px] text-message flex flex-col items-start gap-3 whitespace-pre-wrap break-words [.text-message+\u0026amp;]:mt-5 overflow-x-auto\" data-mce-fragment=\"1\"\u003e\n\u003cdiv class=\"markdown prose w-full break-words dark:prose-invert light\" data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eNicotinamide Adenine Dinucleotide_Reduced (NADH) Raw Material Product Introduction\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003eOur Nicotinamide Adenine Dinucleotide_Reduced (NADH) raw material is a premium-grade supplement ingredient sourced from the highest quality natural sources. NADH is a coenzyme form of vitamin B3, essential for cellular energy production and numerous biological processes in the body.\u003c\/p\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eKey Features:\u003c\/strong\u003e\u003c\/p\u003e\n\u003col data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eEnhanced Cellular Energy:\u003c\/strong\u003e NADH plays a crucial role in the production of adenosine triphosphate (ATP), the primary energy currency of cells. Supplementing with NADH can support optimal cellular energy production, promoting vitality and overall well-being.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eAntioxidant Support:\u003c\/strong\u003e NADH acts as a potent antioxidant, helping to neutralize harmful free radicals and reduce oxidative stress in the body. This antioxidant activity supports cellular health and helps protect against oxidative damage.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eCognitive Function:\u003c\/strong\u003e Research suggests that NADH may support cognitive function and mental clarity by enhancing neurotransmitter synthesis and promoting healthy brain cell function. It may also help improve focus, memory, and overall cognitive performance.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eMitochondrial Health:\u003c\/strong\u003e NADH is essential for mitochondrial function, supporting the health and efficiency of these cellular powerhouses. By optimizing mitochondrial function, NADH contributes to overall cellular health and vitality.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eImmune System Support:\u003c\/strong\u003e NADH plays a role in immune cell function and modulation, supporting a healthy immune response and overall immune system function. It may help enhance the body's ability to defend against pathogens and maintain immune health.\u003c\/p\u003e\n\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eApplications:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eEnergy and Vitality Supplements\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eCognitive Health Formulations\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eAnti-Aging Products\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eImmune Support Nutraceuticals\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003e\u003cstrong data-mce-fragment=\"1\"\u003eWhy Choose Our NADH Raw Material?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul data-mce-fragment=\"1\"\u003e\n\u003cli data-mce-fragment=\"1\"\u003eSuperior Quality: Our NADH raw material is sourced from reputable suppliers and undergoes rigorous testing to ensure purity, potency, and quality.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eScientifically Proven: Backed by scientific research and clinical studies, our NADH raw material is supported by evidence of its efficacy and safety for various health applications.\u003c\/li\u003e\n\u003cli data-mce-fragment=\"1\"\u003eVersatile Formulation: Our NADH raw material can be easily incorporated into a wide range of supplement formulations, offering flexibility and customization options for product development.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp data-mce-fragment=\"1\"\u003eExperience the benefits of NADH for energy, vitality, and overall health with our premium raw material. Contact us today to learn more about our products and how they can enhance your formulations.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e","brand":"Acerchem","offers":[{"title":"Nicotinamide Adenine Dinucleotide_Reduced (NADH)","offer_id":47906776416541,"sku":"","price":1200.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0811\/5047\/6573\/files\/istockphoto-621904108-612x612.jpg?v=1711620902"},{"product_id":"β-nicotinamide-adenine-dinucleotide-nad","title":"β-Nicotinamide Adenine Dinucleotide (NAD+)","description":"Definition:\u003cbr data-mce-fragment=\"1\"\u003eNicotinamide adenine dinucleotide (NAD+) is a coenzyme found in all living cells that plays a critical role in energy metabolism and cellular processes.\u003cbr data-mce-fragment=\"1\"\u003eApplication:\u003cbr data-mce-fragment=\"1\"\u003eNAD+ has been proposed to enhance cellular function and promote overall health.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eForm:\u003cbr data-mce-fragment=\"1\"\u003eWhite to off-white powder.","brand":"acerchem","offers":[{"title":"Default Title","offer_id":47920952803613,"sku":"","price":150.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0811\/5047\/6573\/files\/6483f14a0779c1dc8ae213decb8cd536_7dedccef-c143-4660-ad72-a8ccdbf55e6d.jpg?v=1711728115"},{"product_id":"nicotinamide-riboside-chloride-nr","title":"Nicotinamide Riboside Chloride (NR)","description":"Nicotinamide riboside is a member of the vitamin B3 family. It's found in fruits, vegetables, meat, and milk.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003eNicotinamide riboside is changed in the body to a chemical called NAD+. The body needs NAD+ for many processes to work normally. Low levels can cause health problems. Taking nicotinamide riboside can help raise low NAD+ levels.\u003cbr data-mce-fragment=\"1\"\u003e\u003cbr data-mce-fragment=\"1\"\u003ePeople use nicotinamide riboside for anti-aging effects, high cholesterol, high blood pressure, Alzheimer disease, obesity, and many other purposes, but there is no good scientific evidence to support these uses.","brand":"acerchem","offers":[{"title":"Default Title","offer_id":47920960897309,"sku":"","price":90.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0811\/5047\/6573\/files\/6483f14a0779c1dc8ae213decb8cd536_c9b0f6fc-6742-483a-b6bd-23464f257d1c.jpg?v=1711728183"},{"product_id":"β-nicotinamide-mononucleotide-nmn","title":"β-Nicotinamide mononucleotide (NMN) ","description":"β-Nicotinamide mononucleotide (NMN) ，as a precursor to NAD+, primarily functions through NAD+ in the body. By elevating intracellular NAD+ levels, NMN participates in and optimizes various biological processes including energy generation, DNA repair, and gene expression regulation. This leads to a range of health benefits such as anti-aging, longevity promotion, improved metabolism, cardiovascular maintenance, neural protection, and enhanced muscle function.","brand":"acerchem","offers":[{"title":"Default Title","offer_id":47920985440541,"sku":"","price":110.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0811\/5047\/6573\/files\/6483f14a0779c1dc8ae213decb8cd536_ba68ee4e-1166-424e-9dde-0b7b2d1281dd.jpg?v=1711728329"}],"url":"https:\/\/acerchem.com\/collections\/mitochondrial-energy-healthy-aging.oembed","provider":"Acerchem","version":"1.0","type":"link"}